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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 531 for sleep

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  1. A Study of the Effect of Lack of Sleep on Blood Pressure

    Rochester, MN

  2. Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

    Rochester, MN

  3. Sleep for Stroke Management and Recovery Trial

    Scottsdale/Phoenix, AZ

  4. A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

    Scottsdale/Phoenix, AZ

  5. A Study to Measure the Effectiveness of Environmental Interventions to Reduce Sleep Inertia

    Rochester, MN

  6. A Study to Demonstrate that Acetazolamide is not Inferior to Diazepam for Patients who have Continuous Spike and Wave Brain Pattern in Sleep

    Rochester, MN

  7. A Study to Evaluate Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants with Moderate-to-Severe Allergic Asthma

    Rochester, MN

  8. A Study of the Effects of not Allowing Sleep in Addition to the Usual Care of Hospitalized Patients with Major Depression

    Rochester, MN

  9. A Study of Automated Zonal Control of Indoor Air Pollutants on Cardiopulmonary Health, Sleep Quality, and Comfort in a Simulated Apartment

    Rochester, MN

  10. Monitoring of Sleep and Behavior of Children 3-7 Years Old Receiving Parent-Child Interaction Therapy with the Help of Artificial Intelligence

    Rochester, MN

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