A Study of Automated Zonal Control of Indoor Air Pollutants on Cardiopulmonary Health, Sleep Quality, and Comfort in a Simulated Apartment


About this study

The overarching aim of the study is to understand the health effects of indoor air pollution sources by focusing on controlling emissions from cooking and cleaning, by automating air cleaning devices, exhaust fans, and air handling unit (AHU) supply flow rates based on Internet of Things air quality sensor measurements.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • Individuals 18 years of age or over.
  • Individuals who are a Mayo Clinic employee, contractor, affiliate or volunteer.
  • Individuals with a regular schedule that are not shift work.
  • Ability to reside in  the Well Living Lab for four consecutive weeks, excluding weekends.
  • Be fully vaccinated for COVID-19.
  • Willing to remain in the module until all specimens and measures are completed.
  • Ability to fulfill scripted tasks, including cooking and cleaning.
  • Ability to have blood drawn and urine samples collected.
  • Ability to provide informed consent.

Exclusion Criteria:

  • Individuals who are smokers or having quit smoking < 1 year prior.
  • Individuals who have a respiratory infection
  • Individuals who have signs and symptoms of obstructive pulmonary disease, asthma, heart failure or cardiac arrhythmia.
  • Individuals who use corticosteroids, anti-arrhythmic medication, beta-blockers, anti-inflammatory drugs or aspirin.
  • Women who are pregnant or intend to become pregnant during the duration of the study.
  • Individuals who perform shift work.
  • Individuals who have had a positive COVID-19 test within the last three (3) months OR Individuals who have had a positive COVID-19 test requiring hospitalization OR positive COVID-19 test and still experiencing residual symptoms (e.g., persistent cough, shortness of breath, etc.).

Eligibility last updated 6/20/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Open for enrollment

Contact information:

Cynthia Cassidy M.A., M.B.A.

(507) 266-1621


More information


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