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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 549 for sleep

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  1. Sleep-Related Determinants of Stroke

    Scottsdale/Phoenix, AZ

  2. Optimizing Sleep/Wake Related Cognitive Efficacy

    Rochester, MN

  3. Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

    Rochester, MN

  4. A Study to Investigate the Effectiveness and Safety of Injectafer for the Treatment of Restless Legs Syndrome

    Scottsdale/Phoenix, AZ

  5. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  6. Sleep Extension and Blood Pressure

    Rochester, MN

  7. Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

    Rochester, MN

  8. A Study of the Effect of Lack of Sleep on Blood Pressure

    Rochester, MN

  9. Sleep for Stroke Management and Recovery Trial

    Scottsdale/Phoenix, AZ

  10. A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

    Scottsdale/Phoenix, AZ

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