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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 527 for sleep

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  1. Sleep-Related Determinants of Stroke

    Scottsdale/Phoenix, AZ

  2. A Multicenter Study of the Effectiveness and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) with an Open-label Safety Extension

    Scottsdale/Phoenix, AZ

  3. Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults with Insomnia

    Rochester, MN

  4. Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

    Rochester, MN

  5. Optimizing Sleep/Wake Related Cognitive Efficacy

    Rochester, MN

  6. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  7. A Study to Investigate the Effectiveness and Safety of Injectafer for the Treatment of Restless Legs Syndrome

    Scottsdale/Phoenix, AZ

  8. Sleep Extension and Blood Pressure

    Rochester, MN

  9. A Study of the Effect of Lack of Sleep on Blood Pressure

    Rochester, MN

  10. Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

    Rochester, MN

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