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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 527 for sleep

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  1. Reflex Responses to Intermittent Hypoxia in Humans

    Rochester, MN

  2. A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA

    Scottsdale/Phoenix, AZ

  3. A Study to Determine if a Mask-fitting App Using Facial Recognition Improvea Clinical Care for Patients Using Positive Airway Ppressure Devices?

    Rochester, MN

  4. A Study to Evaluate Sleep for Stroke Management and Recovery

    Rochester, MN

  5. Efficacy of Extended Melatonin on sleep cycle in patients with PD and RBD.

    Jacksonville, FL

  6. A Study of Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea to Prevent Cardiovascular Disease

    Rochester, MN

  7. HELP-HY: Health Education and sLeep Program in HYpertension

    Rochester, MN

  8. Study to Assess the Safety and Effectiveness of Oral BTD-001 in Adults with Idiopathic Hypersomnia

    Scottsdale/Phoenix, AZ

  9. Statins and CPAP in Adipose Tissue of OSA

    Rochester, MN

  10. A Study of the Safety and Effectiveness of JZP-110 in the Treatment of Excessive Sleepiness in Patients with Narcolepsy

    Scottsdale/Phoenix, AZ

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