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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 122 for knee

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  1. A Study to Compare Pain Protocol With and Without Opioids Following Total Joint Arthroplasty

  2. Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

    Rochester, MN

  3. Mobile Educations Effect on Pain Outcomes

    Rochester, MN

  4. A Study Assessing the Impact of a Whole Food Plant-Based Diet for Diabetic Patients Who are Undergoing a Total Joint Replacement

    Scottsdale/Phoenix, AZ

  5. A Study to Evaluate Low-Intensity Blood Flow Restriction Training to Improve Post-Operative Outcomes for ACL Reconstruction

    Scottsdale/Phoenix, AZ

  6. Safety and Pharmacology of SNX-5422 Plus Everolimus in Subjects with Neuroendocrine Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Metal Ion Concentrations After Total Knee Arthroplasty

    Rochester, MN

  8. Ultrasound Assessment of Weightbearing and Non-Weightbearing Meniscal Protrusion

    Rochester, MN

  9. Trial of REcycled CartiLage Auto/Allo IMplantation for the Treatment and Repair of Focal Knee Cartilage Defects (RECLAIM)

    Rochester, MN

  10. Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees

    Rochester, MN

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