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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 122 for knee

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  1. Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees

    Rochester, MN

  2. A Study of Clinical Outcomes Data and Imaging for Patients Receiving Cartiform for Articular Cartilage Defects as Treatment

    Rochester, MN

  3. Effect of Gluteus Maximus Fatigue on Hip and Knee Inter-joint Coordination

    Rochester, MN

  4. Agili-C™ Implant Performance Evaluation

    Rochester, MN

  5. Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis (ARISE)

    Rochester, MN

  6. Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique

    Rochester, MN

  7. Lipogems-processed Microfragmented Adipose Tissue Compared to Saline for the Treatment of Knee Osteoarthritis

    Rochester, MN, Scottsdale/Phoenix, AZ

  8. Study Comparing NOVOCART 3D and Microfracture Surgery for Treatment of Articular Knee Cartilage

    Rochester, MN

  9. Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

    Rochester, MN, Minneapolis, MN

  10. Phase 1b Clinical Trial to Evaluate PEP and EUFLEXXA for Knee Osteoarthritis (KOA)

    Scottsdale/Phoenix, AZ, Rochester, MN

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