Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees


About this study

This study will assess if the functional performance and musculoskeletal outcome of transfemoral amputees are improved after receiving a Microprocessor Knee (MPK) compared to a Non-Microprocessor Knees (NMPK).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

This study is ongoing, but not recruiting participants

Inclusion Criteria:

  • Unilateral transfemoral amputee
  • Medicare Functional Classification Level K2 or K3
  • Currently using NMPK prosthesis
  • No current residual limb problems, such as skin breakdown
  • Able to ambulate without a gait aid

Exclusion Criteria:

  • Previous neuromuscular complications currently affecting gait
  • Currently undergoing dialysis treatments
  • Amputation of the contralateral limb
  • Poor fit of current NMPK prosthesis

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Kenton Kaufman, Ph.D.

Closed for enrollment

More information


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