Evaluating The Efficacy Of A "Quiet Knee Protocol" In Primary Total Knee Arthroplasty (TKA): A Prospective Randomized Study

Overview

About this study

The goal of this randomized clinical trial is to access the following:

1. Compare the effectiveness of the QKP versus a standard rehabilitation protocol in improving postoperative pain control, ROM, and functional recovery following primary TKA.
2. Assess whether the QKP reduces reliance on formal PT services.
3. Evaluate the impact of QKP on secondary outcomes, including opioid consumption, manipulation under anesthesia (MUA) rates, and patient satisfaction scores.

Patients will be randomized into either a standard of care arm vs QKP rehabilitation protocol arm. Each group will answer questionnaires and be followed for 12 months.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

* Adults (≥18 years) undergoing unilateral primary TKA for osteoarthritis
* Willingness to adhere to the assigned rehabilitation protocol
* Ability to provide informed consent

Exclusion Criteria:

* Revision TKA or bilateral procedures
* Preexisting neuromuscular disorders affecting mobility
* Prior knee surgery within 12 months
* No Joint Hardware
* Agree to avoid plane trips post-surgery for 2 weeks
* Patients with 100-degree flexion contracture
* Pregnant subjects

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Niall Cochrane, M.D.

Open for enrollment

Contact information:

Orthopedic Research Clinical Unit

(507) 266-6402

ORCU@mayo.edu

More information

Publications

Publications are currently not available