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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 57 for genomics

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  1. A Study to Evaluate Myeloma-Developing Regimens Using Genomics (MyDRUG)

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. A Phase I study of Epalrestat Therapy in a Single Patient with Phosphomannomutase Deficiency (PMM2-CDG)

    Rochester, MN

  3. A Study to Evaluate the Use of Genomic Sequencing in Clinical Practice

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Myocardial Infarction Genes (MI-GENES) Study

    Rochester, MN

  5. A Study to Assess the MEK Inhibitor Mirdametinib (PD-0325901) in Patients with Neurofibromatosis Type 1 Associated Plexiform Neurofibromas

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. Study to Determine Effectiveness of Dietary Monosaccharide Supplementation in Patients with Congenital Disorders of Glycosylation

    Rochester, MN

  7. Study of HPN536 in Patients with Advanced Cancers Associated With Mesothelin Expression

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

    Rochester, MN

  9. A Study of the Safety and Effectiveness of (+) Epicatechin for Treating Patients with Friedreich's Ataxia

    Rochester, MN

  10. Impact of Estradiol Addback

    Rochester, MN

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