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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 56 for genomics

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  1. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

    Rochester, MN

  2. A Study of Clinical Symptoms in PMM2 Patients Affected by mtDNA Variants and Haplotypes

    Rochester, MN

  3. A Study of Transplant Organ Genomics to Help Prevent Rejection in Kidney Transplant Recipients with Realtime Assay Monitoring

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Testing of Real-Time Diagnostic Platform (HPView) for the Detection of High-risk HPV Strains in Urine

    Rochester, MN

  5. A Study to Evaluate Immune Regulation at the Point Where Maternal Genes and Fetus Genes Meet in the Human Placenta

    Rochester, MN

  6. Testing the Biochemical Behavior of the Fecal Microbiome

    Rochester, MN

  7. Hyperammonemia in Patients undergoing Roux-en-Y Gastric Bypass Surgery

    Rochester, MN

  8. A Study of Vaginal Microbial Signatures for Women with Refractory Symptoms of Bacterial Vaginosis or Vaginitis

    Rochester, MN

  9. A Study to Establish a Patient Clinical and Genetic Information Database to Better Characterize Symptoms and Causes of Angelman Syndrome

    Rochester, MN

  10. A Study of Genetic Testing in the Care of Glioma Patients

    Rochester, MN

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