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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 43 for genomics

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  1. A Study to Evaluate Immune Regulation at the Point Where Maternal Genes and Fetus Genes Meet in the Human Placenta

    Rochester, MN

  2. A Study to Establish a Patient Clinical and Genetic Information Database to Better Characterize Symptoms and Causes of Angelman Syndrome

    Rochester, MN

  3. Visual Outcomes in Patients with Neurofibromatosis Type 1

    Rochester, MN

  4. Microbiome on Neckties from Hospital Staff

    Rochester, MN

  5. Testing the Biochemical Behavior of the Fecal Microbiome

    Rochester, MN

  6. A Study to Explore Clinicians’ Point-Of-Care Decision-Making Process and Behavior following a Pharmacogenomics Alert

    Rochester, MN

  7. A Study Evaluating the Diagnosis of an X & Y Chromosome Variation

    Rochester, MN

  8. A Study to Analyze the Microbiome and Immunology of the Lower and Upper Female Reproductive Tract in Women with Endometriosis

    Rochester, MN

  9. A Study of Vaginal Microbial Signatures for Women with Refractory Symptoms of Bacterial Vaginosis or Vaginitis

    Rochester, MN

  10. Hyperammonemia in Patients undergoing Roux-en-Y Gastric Bypass Surgery

    Rochester, MN

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