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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 54 for genomics

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  1. A Study of Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumors that are Recurrent or Cannot Be Removed by Surgery

    Rochester, MN

  2. Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine

    Rochester, MN

  3. A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  4. Gemini Study to Evaluate the Integration of Cancer Genetic Testing into a Cancer Clinical Practice at Mayo Clinic at Arizona

    Scottsdale/Phoenix, AZ

  5. Hearing Genomics

    Rochester, MN

  6. Mayo Clinic Cancer Genomics Service Line Biorepository

    Eau Claire, WI, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Beta Testing of the Mayo Clinic GeneGuide Application for Targeted Genomic Testing and Genomics Education

    Rochester, MN

  8. Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study of Clinical Symptoms in PMM2 Patients Affected by mtDNA Variants and Haplotypes

    Rochester, MN

  10. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

    Rochester, MN

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