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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 83 for genomics

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  1. The TOGETHER Project - Transplant Organ Genomics to Help Prevent Rejection in Heart Transplant Recipients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Transplant Organ Genomics to Help Prevent Rejection in Kidney Transplant Recipients – RNA-seq Signature Validation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study Investigating Integrated Genomics and Patient-derived Cancer Models

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate Patient Experience and Satisfaction with Predictive Genomic Testing Ordered Through SL3

    Rochester, MN

  5. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

    Rochester, MN

  6. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

    Rochester, MN

  7. A Study of Clinical Symptoms in PMM2 Patients Affected by mtDNA Variants and Haplotypes

    Rochester, MN

  8. A Study to Analyze Intracerebral Hemorrhage Hematoma

    Jacksonville, FL

  9. A Study of Transplant Organ Genomics to Help Prevent Rejection in Kidney Transplant Recipients with Realtime Assay Monitoring

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Natural History Study Protocol in PMM2-CDG (CDG-Ia)

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