CCaTS-CIM-CBD Precision Medicine Award

The Precision Medicine Award, from the Mayo Clinic Center for Clinical and Translational Science (CCaTS), the Center for Individualized Medicine (CIM) and the Center for Biomedical Discovery (CBD), offers funds to support research on rare diseases at Mayo Clinic.

The Precision Medicine Award is designed to support projects that will lead to applications for extramural funding.

The scope of projects supported by the Precision Medicine Award may include any step of the basic to translational to clinical research continuum. Projects proposing the use of CIM Programs and Services (must be logged in to the Mayo Clinic network) are encouraged. Applicants are particularly encouraged to review the information available on the CIM Clinomics Program webpage.

Eligibility

Associate consultants, senior associate consultants and consultants from across Mayo Clinic are eligible for the Precision Medicine Award. Individuals in the process of transitioning from mentored career development awards to independent awards are encouraged to apply.

Projects proposed should be focused on advancing knowledge of the diagnosis, treatment or mechanisms underlying rare disease.

Funding

CCaTS, CIM and CBD anticipate funding up to two awards from this request for applications. Awards provide up to $50,000 a year (direct costs plus indirects) for one year. Extensions are considered only under extenuating circumstances.

Unallowable expenses include capital equipment and computers or laptops.

Recipients of grants or awards supported by CCaTS may be asked to review applications for other CCaTS grants.

Application information

Timeline

Pre-applications (previously called letters of intent) are due by 5:00 p.m. Central time on Feb. 12, 2020. They should be submitted through the START Application Tool (must be logged in to the Mayo Clinic network). Pre-applications must include the CIM checklist (Word document).

Applicants are invited to submit full applications after review of the pre-applications. Applications are due by 5:00 p.m. Central time on April 1, 2020. They should be submitted through the START Application Tool (must be logged in to the Mayo Clinic network).

The anticipated award date is July 1, 2020.

Full application requirements

Applicants are required to include the following as attachments with their full applications:

  • Biosketches for faculty team members using the NIH's new biographical sketch format
  • Brief budget justification
  • Letter(s) of support (if applicable)

A formal Mayo Integrated Research Information System (MIRIS) budget prepared by the Office of Sponsored Projects Administration (OSPA) is not required at the time of application. If the project is selected for funding, the awardee will work with Susan (Sue) J. Rubow and OSPA to create a MIRIS funding proposal and budget.

Review criteria

CCaTS, CIM and CBD apply the following criteria when reviewing applications for the Precision Medicine Award:

  • Scientific merit, with a strong emphasis on impact and innovation
  • Likelihood of future extramural funding
  • Feasibility within the time and budget proposed
  • Qualifications of the investigators
  • CIM checklist completed

Prior approval for research involving human participants

Awardees with projects involving human participants are required to submit information to the National Center for Advancing Translational Sciences (NCATS) to obtain prior approval before conducting any activities related to human participants. Documentation includes a Human Subject Plan. CCaTS staff members guide awardees through the process and provide assistance.

Reporting

Annual progress reports are required for up to two years beyond the end date of the award.

Publications

The NIH Public Access Policy requires that all publications resulting from NIH funding be uploaded to PubMed Central. Recipients of CCaTS awards, including intramurally funded awards, must follow this policy. The Mayo Clinic Public Access Policy intranet site (must be logged in to the Mayo Clinic network) guides awardees through the process of uploading publications.

Please remember to cite the Mayo Clinic CCaTS in your publication.

Contact

For scientific questions, email Robert J. Pignolo, M.D., Ph.D., Richard Weinshilboum, M.D., or Mark A. McNiven, Ph.D.

For questions about the request for applications or the START Application Tool, email Susan (Sue) J. Rubow.