CCaTS: Accelerating discoveries toward better health
Mayo Clinic Center for Clinical and Translational Science (CCaTS) is funded by the National Institutes of Health (NIH) Clinical and Translational Science Awards (CTSA) program, grant numbers UL 1TR002377, KL 2TR0002379 and TL 1TR002380, from the National Center for Advancing Translational Sciences (NCATS).
CCaTS is a central hub for institutional advancement of research and education at Mayo Clinic. The center provides tools and expert consultation to support every aspect of medical research, including basic discovery science, clinical and community-engaged research, and late-stage application and commercialization. As a member of the national CTSA program, CCaTS joins a national network of medical research institutions collaborating to transform how clinical and translational research is conducted nationwide.
Mayo Clinic CCaTS is led by Sundeep Khosla, M.D., principal investigator and director of CCaTS, and dean for clinical and translational science at Mayo Clinic. David O. Warner, M.D., is co-principal investigator and associate director of CCaTS, and is also principal investigator of the KL2 mentored career development grant. Anthony J. Windebank, M.D., is principal investigator of the TL1 predoctoral training grant.
The content of this website is solely the responsibility of Mayo Clinic CCaTS and does not necessarily represent the official views of the NIH.
News
Supplemental grants to fund opioid and artificial intelligence research
The National Center for Advancing Translational Sciences (NCATS) recently awarded funding to two administrative supplements to the National Institutes of Health Clinical and Translational Science Awards program grant (UL1 TR002377) that supports Mayo Clinic CCaTS.
The supplements fund specific areas of clinical and translational research focused on meeting unmet patient needs and training current and future generations of clinical investigators. The research team of Hongfang Liu, Ph.D., and Jennifer St. Sauver, Ph.D., is using data science to understand the opioid crisis, while the team led by Rickey E. Carter, Ph.D., and Eric C. Polley, Ph.D., is developing artificial intelligence training for investigators.
Read more
Mentorship program makes research aspirations a reality
Mayo Clinic hematologist and KL2 scholar Mrinal S. Patnaik, M.B.B.S., talks about his reasons for going into research and taking on a dual career as a physician and independent investigator. "I was inspired to pursue research to help find solutions to unmet patient needs I saw in my work as a clinician," he says. Through CCaTS' KL2 Mentored Career Development Program, he's learning the skills he needs to find answers and advance the field of medicine.
Read more on Mayo's Advancing the Science blog.
Popular films spark community dialogue about biomedical ethics
"Bioethics at the Cinema," organized by the Mayo Clinic Biomedical Ethics Research Program and the Rochester Public Library, uses popular films to create community dialogues around important biomedical ethics issues. A recent screening of "Wonder," the story of a 10-year-old boy living with a rare genetic condition, sought to inspire kindness and appreciation for difference.
Read more on Mayo's Advancing the Science blog.
Precision genomics point the way to mutations associated with accelerated aging
"We're using precision genomics like a heat-seeking missile," says Dr. Patnaik, a Mayo Clinic hematologist and clinical researcher. "Not to destroy, but to zero in on genetic mutations that may be linked with short telomere and other inherited bone marrow failure syndromes, providing unique insights into their disease biology."
Read more on the Mayo Clinic News Network.
After grant renewal, CCaTS abuzz with activity
In October 2017, the NIH renewed Mayo Clinic Clinical and Translational Science Award from the National Center for Advancing Translational Sciences — an award totaling $48.8 million over five years. This renewal allows Mayo Clinic to continue pursuing its long-term goals in clinical and translational science, while also setting new short-term objectives.
Read more on Mayo's Advancing the Science blog.
CCaTS director receives frontiers in science award
Dr. Khosla has received the 2018 American Association of Clinical Endocrinologists Frontiers in Science Award. This award recognizes his contributions to the field of endocrinology. Dr. Khosla is the director of Mayo Clinic CCaTS and is the chair of research for Mayo's Division of Endocrinology, Diabetes, Metabolism and Nutrition.
Read more on the Mayo Clinic News Network.