Translational impact

Mayo Clinic's Center for Clinical and Translational Science (CCaTS) prepares researchers and research teams to move discoveries through the translational spectrum. Through TL1- and KL2 -supported workforce development cross-program training activities, pilot awards, and resources and services, CCaTS supports investigators and teams who are advancing clinical and translational science at Mayo Clinic and across the broader research community.

Building a translational science workforce

CCaTS workforce programs prepare investigators, trainees and research professionals to address barriers that slow the movement of discoveries into practice. Training emphasizes the core characteristics of translational scientists, including rigorous research, team science, systems thinking, boundary crossing, communication, process innovation and leadership.

Publications

Explore these publications:

Highlighted impact publications

CCaTS support connects learners and research teams with practical experience and resources in artificial intelligence and data literacy, community-engaged research, clinical trial innovation, implementation science, regulatory navigation, rural health research, and dissemination. This approach reflects the center's broader goal of helping researchers and research teams develop solutions that are rigorous, scalable and relevant to real-world health needs.

View selected publications that demonstrate the reach and influence of CCaTS:

3D model of the human brain on dark background surrounded by neural networks. Bipolar disorder

Singh B, Swartz HA, Cuellar-Barboza AB, Schaffer A, Kato T, Dols A, Sperry SH, Vassilev AB, Burdick KE, Frye MA. "Bipolar Disorder." Lancet. 2025.

Many hands gathered together. Community-engaged research

Dugani SB, Tilburt JC, White RO, Sabey EJ, Abbenyi A, Heendeniya N, Stephenson N, Brockman TA, Albertie M, Murrell D, Meiners L, Nichols R, Aleman M, Karuppana S, Elworth J, Brewer LC, Odedina F, Patten CA, Adsul P, Wallerstein NB, Garovic VD, Sia IG, Wieland ML. "Mayo Clinic Framework for Community-Engaged Research: Development, Implementation, and Impact." Mayo Clinic Proceedings. 2026.

Artificial intelligence researchers working together with touch screen tablet. Artificial intelligence and data literacy

Zand J, Suvakov M, Overgaard SM, Kozikowski CG, Jimison RC, Nelson KB, Silvano CJ, Meiners LM, Fan JW, Schultz KE, Carter RE, Wieland ML, Patten CA, Dugani SB, Weis JA, Poe JD, Holmes DR 3rd, Griffiths LG, Dieter HL, Juhn YJ, Enders FT, Callstrom MR, Shah V, Meyer FB, Garovic VD. "Building Artificial Intelligence and Data Literacy Across the Health Care Research Workforce in the Mayo Clinic Center for Clinical and Translational Science: Why It Matters and What We Are Doing About It." Mayo Clinic Proceedings. 2026.

Digital rendering of a computer processor. Large language models

Zand J, Suvakov M, Overgaard SM, Silvano CJ, Meiners LM, Fan JW, Carter RE, Wieland ML, Patten CA, Dugani SB, Dieter HL, Wi CL, Juhn YJ, Enders FT, Callstrom MR, Shah VH, Garovic VD. "The Evolving Role of Large Language Models in Healthcare Research and Scientific Communication." Mayo Clinic Proceedings. 2026.

Hand holding web with text reading Clinical trial program

Haddad TC, Mercado LA, Le-Rademacher JG, Enarson DA, Sener U, Kumar A, Price KA, Juhn YJ, Cartin-Ceba R, Colon-Otero G, Willman CL, Garovic VD, Kottschade RS. "A Multiregional Decentralized Clinical Trial Program to Improve Access." JAMA Network Open. 2026.

A small 'Hospital' sign is shown outdoors in a rural area. Rural health

Brockman TA, McGuinness A, Elworth JT, Sabey E, Sedarski R, Lee S, Petersen C, Clark J, Breeden B, Patten CA. "Community Engagement Contributions to Rural Health Research: Researchers' Experience With the Midwest Rural Health Research Community Advisory Board." Journal of Clinical and Translational Science. 2025.

Translational impact beyond publication

CCaTS evaluates impact beyond traditional publication counts. Workforce and research outcomes include:

  • Trainee progression.
  • Independent funding.
  • Leadership roles.
  • Clinical trial activity.
  • Community partnerships.
  • Policy and guideline influence.
  • Dissemination of tools and frameworks.
  • Contributions to scalable translational science methods.

This broader view of impact reflects that CCaTS aims to produce not only individual research projects but also people, teams, models and infrastructure that help discoveries reach patients, communities and health systems more effectively.

Learn more about CCaTS evaluation.