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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 129 for transplant

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  1. Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

    Rochester, MN

  2. Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) (INFUSE)

    Rochester, MN

  3. Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant

    Jacksonville, FL

  4. AML: Treatment of Relapse after Transplant or Extended Maintenance of Remission – Investigational Study (ARTEMIS) Effectiveness of MT-401 in Patients with AML Following Stem Cell Transplant

    Jacksonville, FL, Rochester, MN

  5. A Study to Develop and Validate Hybrid Molecular Imaging to Transform the Care of Hepatocellular Carcinoma Patients

    Rochester, MN

  6. A Study to Evaluate Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

    Rochester, MN

  7. Testing the Addition of Ixazomib to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial

    Rochester, MN

  8. Treating Adult Patients with Primary Sclerosing Cholangitis with Oral Vancomycin in a Randomized Trial

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study of Short-term Survival in Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%

    Rochester, MN

  10. Feasibility of Autologous Adipose-derived Stromal Cells from Stromal Vascular Fraction (SVF) to Treat Adults with Pressure Ulcers or Diabetic Foot Ulcers

    Jacksonville, FL

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