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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 131 for transplant

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  1. A Study to Evaluate the Safety and Effectiveness of MGTA-145 Combined with Plerixafor for Transplantation of Stem Cells in Recipients with Hematological Malignancies

    Rochester, MN

  2. A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation

    Jacksonville, FL

  3. A Study to Evaluate Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients with Dyskeratosis Congenita

    Rochester, MN

  4. A Study to Examine The Effectiveness, Feasibility, and Acceptability of Exercise Intervention on Frailty After Kidney Transplantation.

    Rochester, MN

  5. Concomitant Renal and Urinary Bladder Allograft Transplantation

    Rochester, MN

  6. Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

    Rochester, MN

  7. Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

    Rochester, MN

  8. A Study to Evaluate the Safety and Effectiveness of Autologous Cells Expressing Anti-CD20 and Anti-CD19 in Relapsed/Refractory Diffuse Large B Cell Lymphoma Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. A Study to Evaluate the Safety and Tolerability of Rebiotix RBX2660 (microbiota suspension) in Subjects with Recurrent Clostridium difficile Infection

    Rochester, MN

  10. Coping with Hematopoietic Stem Cell Transplantation and Psychosocial

    Scottsdale/Phoenix, AZ

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