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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 124 for transplant

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  • Study status: Open/Status Unknown
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  1. Hematopoietic Stem Cell Transplant Survivors Study (HTSS Study)

    Rochester, MN

  2. Hydroxocobalamin as a New and Possibly Superior Treatment for Refractory Vasoplegic Syndrome during Liver Transplant Surgery

    Jacksonville, FL

  3. Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

    Rochester, MN

  4. A Study to Evaluate Wellness Coaching for Caregivers of Thoracic Transplant Candidates

    Rochester, MN

  5. Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases

    Rochester, MN

  6. A Study to Assess the Efficacy, Safety, and Tolerability of Oral LPCN 1148 in Male Subjects With Cirrhosis of the Liver and Sarcopenia

    Scottsdale/Phoenix, AZ

  7. A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation

    Jacksonville, FL

  8. A Study to Evaluate Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients with Dyskeratosis Congenita

    Rochester, MN

  9. A Study of Axatilimab at 3 Different Doses in Patients With Chronic Graft Versus Host Disease (cGVHD)

    Jacksonville, FL, Rochester, MN

  10. Concomitant Renal and Urinary Bladder Allograft Transplantation

    Rochester, MN

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