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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 61-70 of 129 for transplant

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  1. Donor-derived Cell-free DNA Testing in Kidney Transplant Recipients on Reduced Immunosuppression

    Scottsdale/Phoenix, AZ

  2. A Study to Examine Diabetes Control and Patient Reported Outcomes Among Kidney Transplant Recipients with Type 2 Diabetes

    Rochester, MN

  3. A Study to Identify Physical Function Trajectories and Biomarkers after Kidney Transplantation

    Rochester, MN, Jacksonville, FL, Scottsdale/Phoenix, AZ

  4. A Study to Analyze Fractures and Bone Disease in Living Kidney Donors

    Rochester, MN

  5. Iron-Immune System Interaction Shapes Renal Allograft Outcomes After Infections

    Scottsdale/Phoenix, AZ

  6. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    Scottsdale/Phoenix, AZ

  7. Heart Failure and Cardiothoracic Transplant Biorepository

    Rochester, MN

  8. A Study to Evaluate RNA Transcriptomics for Predicting Allograft Failure or Rejection

    Rochester, MN

  9. Fecal Microbiome Transplant National Registry

    Rochester, MN

  10. A Study to Develop a Database of Pancreas Transplant Recipients, to Form a Larger Cohort for Future Research

    Rochester, MN

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