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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 131 for transplant

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  1. Feasibility and Safety of Allogeneic Adipose Mesenchymal Stem Cells (aMSCs) Delivery Into Kidney Allografts Procured from Deceased Donors with High Kidney Donor Profile Index (KDPI)

    Jacksonville, FL

  2. A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation (FREEDOM-1)

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. Cellular Immunotherapy for Viral Induced Cancer - EBV Positive Lymphomas

    Rochester, MN

  4. A Study to Evaluate Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

    Jacksonville, FL

  5. A Study to Evaluate Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS)

    Scottsdale/Phoenix, AZ

  6. J&J Vaccine Booster in Transplant Recipients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) (INFUSE)

    Rochester, MN

  8. Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant

    Jacksonville, FL

  9. A Study to Develop and Validate Hybrid Molecular Imaging to Transform the Care of Hepatocellular Carcinoma Patients

    Rochester, MN

  10. A Study to Evaluate Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

    Rochester, MN

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