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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 132 for transplant

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Daratumumab in Treating Transplant-Eligible Participants with Multiple Myeloma

    Jacksonville, FL

  2. Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

    Rochester, MN

  3. Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant

    Rochester, MN

  4. Study of Iomab-B Prior to HCT vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory AML

    Jacksonville, FL, Rochester, MN

  5. A Study to Compare Standard-Dose Combination Chemotherapy with High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Resistant Germ Cell Tumors

    Rochester, MN

  6. Coping with Hematopoietic Stem Cell Transplantation and Psychosocial

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate the Safety and Tolerability of Rebiotix RBX2660 (microbiota suspension) in Subjects with Recurrent Clostridium difficile Infection

    Rochester, MN

  8. Feasibility and Safety of Allogeneic Adipose Mesenchymal Stem Cells (aMSCs) Delivery Into Kidney Allografts Procured from Deceased Donors with High Kidney Donor Profile Index (KDPI)

    Jacksonville, FL

  9. A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation

    Rochester, MN, Scottsdale/Phoenix, AZ

  10. Cellular Immunotherapy for Viral Induced Cancer - EBV Positive Lymphomas

    Rochester, MN

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