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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 1342 for surgery

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  1. Use of Remote Monitoring to Improve Physician Monitoring, Patient Satisfaction, and Predict Readmissions Following Cardiac Surgery

    Rochester, MN

  2. High Ankle Block Versus Regional Block for Acute Pain Control After Ankle Surgery

    Jacksonville, FL

  3. A Study of the Effect of Probiotic Supplements on Weight Loss, and the Connection it has to the Bacterial Environment of the Digestive System after Bariatric Surgery

    Rochester, MN

  4. Reducing Smoke Exposure in Children Facing Surgery

    Rochester, MN

  5. A Study Using Lactated Ringer's Solution versus 5%Human Albumin in Cardiac Surgery Patients

    Rochester, MN

  6. Phase III Study to Evaluate the Efficacy and Safety of the INTERCEPT Blood System for Red Blood Cells in Patients Undergoing Complex Cardiac Surgery Procedures

    Rochester, MN

  7. The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

    Rochester, MN

  8. A Study to Evaluate a Handheld Dynamometer During Awake Craniotomy

    Jacksonville, FL

  9. A Study to Determine the Impact of Ascorbic Acid Treatment on Vasodilation in Cardiac Surgery

    Rochester, MN

  10. Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery

    Rochester, MN

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