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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 1342 for surgery

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  1. Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery

    Rochester, MN

  2. Feasibility of Use of BariCare App in Pre-bariatric Surgery.

    Rochester, MN

  3. A Study for Optimizing the Timing of Coronary Artery Bypass Surgery in Patients with Acute Coronary Syndrome and Treated with Ticagrelor

    Rochester, MN

  4. A Study to Evaluate The Use of Intravenous Fluorescein Sodium (FS) and YELLOW 560 nm Microscope Filter (YE560) During Surgery for Vestibular Schwannomas (VS)

    Rochester, MN

  5. An Open-Label Study of XOMA 358 in Patients With Hypoglycemia After Gastric Bypass Surgery

    Rochester, MN

  6. A Study of Automated Myocardial Performance Index Before, During and After Fetal Surgeries using Samsung HERA W10

    Rochester, MN

  7. A Study of Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumors that are Recurrent or Cannot Be Removed by Surgery

    Rochester, MN

  8. A Study of Vagus Nerve Blocking for Obesity Control

    Rochester, MN

  9. A Study to Evaluate Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery

    Rochester, MN

  10. A Study for Prevention, Early Detection and Intervention in Acute Kidney Injury Related to Post-Coronary Artery Bypass Grafting Surgery (CABG)

    Rochester, MN

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