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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 1342 for surgery

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  1. Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications

    Rochester, MN

  2. A Study to Evaluate Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery

    Rochester, MN

  3. A Pilot Study to Evaluate the Contribution of the Saphenous Nerve in Ankle Pain of Patients With Degenerative Joint Disease of the Ankle

    Jacksonville, FL

  4. Pilot Trial FETO for CDH

    Rochester, MN

  5. A Study Assessing Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and Neck Using the da Vinci Robotic Surgical System

    Rochester, MN

  6. A Study to Use a Patient Monitoring Application that Monitors Physiological Data, Psychosocial Data, and Responses to Survey Questions in Patients Undergoing Cranial or Spinal Surgery

    Rochester, MN

  7. The eMESH 1 Feasibility Study

    Rochester, MN

  8. A Study of the Effectiveness of Behavior Therapy on Weight Loss with Bariatric Surgery

    Rochester, MN

  9. A Study for the Treatment of Primary Obesity

    Rochester, MN

  10. Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

    Rochester, MN

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