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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1021-1030 of 2194 for surgery

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  1. A Study to Evaluate the Efficacy and Safety of CLBS16 in Subjects with Coronary Microvascular Dysfunction and Without Obstructive Coronary Artery Disease

    Rochester, MN

  2. Real-Time Myocardial Perfusion Echocardiography in the ICU

    Rochester, MN

  3. Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects With Elevated Risk

    Scottsdale/Phoenix, AZ

  4. A Study of Endoscopic Intragastric Balloon Placement for Weight Loss in Liver Transplant Waitlist Candidates

    Rochester, MN

  5. An Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil

    Rochester, MN

  6. A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)

    Rochester, MN

  7. A Study to Analyze the Amount of Antibiotic Absorbed into Tissues Comparing Two Different Modes of Administration

    Scottsdale/Phoenix, AZ

  8. Study to Evaluate the Safety and Effectiveness of IW-1973 Dosing over 12 Weeks in Patients with Congestive Heart Failure with Preserved Ejection Fraction

    Scottsdale/Phoenix, AZ

  9. A Study to Investigate the Performance of Dual Energy CT for the Detection of Breast Implant Rupture and Extra-capsular Silicone Compared to Standard MRI Exams.

  10. A Study of Continuous Simultaneous Recording of Skin Sympathetic Nerve Activity and Electrocardiography for Predicting the Sudden Start of Ventricular Arrhythmia Events and Response to Treatment

    Rochester, MN

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