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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1031-1040 of 2188 for surgery

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  1. Outcomes of Advanced Practice Providers Focused Cardiac Ultrasound Training

    Scottsdale/Phoenix, AZ

  2. Heart Sounds Measurement Using The Wearable Cardioverter Defibrillator In Hospitalized Acute Heart Failure Patients

    Scottsdale/Phoenix, AZ

  3. Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation (ENVISAGE-TAVI AF)

    Rochester, MN

  4. Real-Time Myocardial Perfusion Echocardiography in the ICU

    Rochester, MN

  5. A Study to Evaluate the Efficacy and Safety of CLBS16 in Subjects with Coronary Microvascular Dysfunction and Without Obstructive Coronary Artery Disease

    Rochester, MN

  6. A Study to Analyze the Amount of Antibiotic Absorbed into Tissues Comparing Two Different Modes of Administration

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate a Novel Technique to Diagnose Carotid Artery Stenosis

    Rochester, MN

  8. A Study of Subcutaneous ICD Therapy Combined With VT Ablation for the Secondary Prevention of Sudden Cardiac Death

    Rochester, MN

  9. A Study Evaluate the Positive Impact of Canine Therapy on Cardiac Rehab Patient Outcomes

  10. A Study to Evaluate Effectiveness of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)

    Jacksonville, FL

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