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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1041-1050 of 2194 for surgery

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  1. Real-Time Myocardial Perfusion Echocardiography in the ICU

    Rochester, MN

  2. Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation (ENVISAGE-TAVI AF)

    Rochester, MN

  3. Predicting VO2max and Ventilatory Threshold from the 6 Minute Walk Test

    La Crosse, WI

  4. Outcomes of Advanced Practice Providers Focused Cardiac Ultrasound Training

    Scottsdale/Phoenix, AZ

  5. Heart Sounds Measurement Using The Wearable Cardioverter Defibrillator In Hospitalized Acute Heart Failure Patients

    Scottsdale/Phoenix, AZ

  6. A Study to Evaluate AuTophagy Activation for Cardiomyopathy Due to Anthracycline tReatment

    Rochester, MN

  7. MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

  8. A Study Using Spinal Stimulation During Exercise in Patients with Heart Failure

    Rochester, MN

  9. Use of Cardiac Magnetic Resonance Imaging (cMRI) and Echocardiogram to Diagnose Constrictive Pericarditis and Restrictive Cardiomyopathy

    Rochester, MN

  10. Connected Health Care in Exercise Program for Obesity

    Scottsdale/Phoenix, AZ

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