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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 759 for cardiovascular

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  1. A Study of Minimally Invasive Pericardiotomy as a New Treatment for Heart Failure

    Rochester, MN

  2. Inhaled Sodium Nitrite On Heart Failure With Preserved Ejection Fraction

    Rochester, MN

  3. TOCCASTAR - TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation

  4. A Study of Lower Body Negative Pressure for Research and Development on Non-Invasive Monitoring Devices

    Rochester, MN

  5. A Study Evaluate the Positive Impact of Canine Therapy on Cardiac Rehab Patient Outcomes

    La Crosse, WI

  6. A Study to See if Clinical Cardiac MRI Scanning Can Cause DNA Damage

    Rochester, MN

  7. Colchicine and CRP in Atrial Fibrillation and AF Ablation

  8. Complex Aortic Aneurysm Repair With Fenestrated Stent Grafts

    Rochester, MN

  9. Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

    Rochester, MN

  10. Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient After Minimally Invasive Repair

    Scottsdale/Phoenix, AZ

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