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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 261-270 of 846 for cardiovascular

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  1. A Study Comparing Air versus Blood with Saline as Contrast Shading for Echocardiographic Imaging of the Right Heart and Shunts

    Rochester, MN

  2. Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim 2)

    Rochester, MN

  3. A Study to Evaluate Dapagliflozin to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure

    Rochester, MN

  4. A Study on Pulmonary Mechanics of Playing Wind Instruments

    Rochester, MN

  5. Diagnostic Ultrasound in the Evaluation of Athletes with Vocal Cord Dysfunction

    Rochester, MN, Minneapolis, MN

  6. A Study to Evaluate Breathing Muscle Training in Cardiac Rehab

    Rochester, MN

  7. The PARTNER 3 - AVIV Trial

    Rochester, MN

  8. Assessment of Coronary Plaque Composition Using Optical Coherence Tomography

    Rochester, MN

  9. A Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure

    Rochester, MN

  10. A Study of the Use of the Hansen Medical System in Patients with Paroxysmal Atrial Fibrillation

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