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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-18 of 18 for Pain Medicine

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  1. A Study to Evaluate Resting State Connectivity in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Pain

    Rochester, MN

  2. A Study to Assess Study Design and Potential Willingness to Participate in a Future Study of Opioid Tapering

    Eau Claire, WI, Rochester, MN

  3. Pediatric Pain Rehabilitation Program

    Rochester, MN

  4. Effect of Opioid Use and Fibromyalgia on Steroid Metabolome and Adrenal Function

    Rochester, MN

  5. A Study to Evaluate Analgesic Use and Duration for Pediatric Long Bone Fractures

    Rochester, MN

  6. A Study to Evaluate Prevalence of Secondary Adrenal Insufficiency in Patients with Chronic Pain

    Jacksonville, FL

  7. A Study to Investigate the Use of Diaphragm Muscle Ultrasound to Assess the Duration of a Diaphragm Nerve Block

    Rochester, MN

  8. Pediatric Pain Rehabilitation Treatment Outcomes for Chronic Noncancer Pain

    Rochester, MN

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