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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 18 for Pain Medicine

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  • Study status: Open/Status Unknown
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  1. A Study of Quality of Life and Pain Control Before and After Endovascular Renal Denervation in Individuals with Refractory Kidney Pain

    Rochester, MN

  2. A Study of Lofexidine for Rapid Opioid Tapering in Adults

    Rochester, MN

  3. A Study to Evaluate Patient Experience Comparing Tonic vs. Burst Spinal Card Stimulation for Chronic Pain

    Jacksonville, FL

  4. A Study of the Use of Shear Wave Elastography with an Ultrasound Scanner to Measure Myofascial Trigger Points

    Rochester, MN

  5. Dorsal spInal cord STImulatioN vs mediCal management for the Treatment of low back pain

    Rochester, MN

  6. A Study to Evaluate Prevalence of Hypogonadism in Patients with Chronic Pain

    Jacksonville, FL

  7. A Study to Implement a Patient-Centered Pain Plan and Standardized Preoperative Pain Education for Patients Undergoing Lumbar Procedures

    Mankato, MN

  8. A Study to Evaluate Unintended Prolonged Opioid Use

    Rochester, MN

  9. A Study to Evaluate Droperidol Use in the Emergency Department and the Effect on QTc

    Rochester, MN

  10. A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder

    Rochester, MN

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