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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 46 for Laboratory Medicine and Pathology

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Performance of Coagulation Laboratory Testing in Children and Young Adults

    Rochester, MN

  2. Placenta, Umbilical Cord, and Umbilical Cord Blood as a Source of Therapeutic Cells

    Rochester, MN

  3. A Study to Compare VerifyNow PRU, Delta PRU, and Vasoactive Stimulated Phosphoprotein Flow Cytometry for Evaluating Clopidogrel Response Before and After Neurointerventional Procedures

    Rochester, MN

  4. A Study of Previously Untreated Patients (PUPs) with Congenital Hemophilia

    Rochester, MN

  5. Adipose Tissue Collection for the Study of Mesenchymal Stromal Cells

    Rochester, MN

  6. Salivary Gland Tumor Banking and Clinical Review

    Rochester, MN

  7. Genotype-Phenotype Correlation in Cardiovascular Disease

    Rochester, MN

  8. A Study of Genetic Testing in the Care of Glioma Patients

    Rochester, MN

  9. Detection of Infection in Arthroplasty

    Rochester, MN

  10. A Study of the Gene Make-up of Heart Tumors

    Rochester, MN

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