A Study to Evaluate the QuantiFERON-TB Gold-Plus Test for Blood Detection of Tuberculosis without Symptoms


About this study

The purpose of this study is to evaluate the new QFT-Plus assay compared to the QFT-Gold assay and the tuberculin skin test results (as available) for the detection of tuberculosis without symptoms in high-risk patients.


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.


Inclusion Criteria

  • A prior diagnosis of Latent Tuberculosis Infection
  • Age ≥ 18 years
  • Undergoing routine screening or follow-up care for active tuberculosis or any form of Latent Tuberculosis
  • Any patient, including those with refugee or immigrant status, receiving medical care at Olmsted Public Health Services

Exclusion Criteria

  • Lack of oral consent
  • No known or suspected active tuberculosis disease

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Elitza Theel, Ph.D.

Contact us for the latest status

Contact information:

John Wilson M.D.



More information


Publications are currently not available

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