Transgenic and Knockout Core

The Mayo Clinic Transgenic and Knockout Core serves as a shared resource within Mayo Clinic Comprehensive Cancer Center.

The Transgenic and Knockout Core generates transgenic and gene-targeted animal models for cancer research projects that explore the underlying causes of cancer.

Transgenic and gene-targeted mouse models enable Mayo Clinic cancer researchers to study in vivo how the overexpression of specific genes and their mutants is involved in the initiation, progression and metastasis of certain types of human cancer.

Learn more about the Mayo Clinic Transgenic and Knockout Core.