The research of Yan W. Asmann, Ph.D., focuses on developing analytical algorithms and frameworks for multi-omics data mining, modeling and integration. Dr. Asmann has applied these methods to study complex disorders and to identify diagnostic-prognostic biomarkers and therapeutic targets. Dr. Asmann collaborates with clinical investigators and laboratory scientists in translational research of several diseases, including women's cancers, multiple myeloma and Alzheimer's disease.
- Multi-omics data integration to study disease etiology, staging, prognoses and treatments
- Cancer neoantigen identification and prioritization for neoantigen-directed immunotherapies
- Models to discover novel therapy options, predict therapy outcomes, and identify patients for drug repurposing
Significance to patient care
Dr. Asmann's research will enable the discovery, validation and clinical application of genomic biomarkers and therapeutic targets in the era of individualized medicine.
- Co-director, Bioinformatics/Biostatistics and Data Management Cores, Multiple Myeloma SPORE, 2021-present
- Co-director, Bioinformatics/Biostatistics Core, Alzheimer's Disease Multi-Center U19, 2021-present
- Member, International Society for Cell and Gene Therapy, 2020-present
- Member, Society for Immunotherapy of Cancer (SITC), 2019-present
- Member, International Society to Advance Alzheimer's Research and Treatment (ISTAART), 2017-present
- Member, American Society of Hematology, 2014-present
- Grant reviewer, National Institutes of Health and Department of Defense, 2011-present
- Member, International Society for Computational Biology, 2010-present