Lewy Body Dementia

Mayo Clinic has published extensively in the area of Lewy body dementia research through the collaboration of these investigators in clinical, pathology, imaging, genetics, biomarker and basic research:

• Clinical — Bradley F. Boeve, M.D., Tanis J. Ferman, Ph.D., Jonathan Graff-Radford, M.D.
• Pathology — Dennis W. Dickson, M.D., and Joseph E. Parisi, M.D.
• Imaging — Kejal Kantarci, M.D.
• Genetics — Owen A. Ross, Ph.D.
• Basic research — Pamela J. McLean, Ph.D.
• Biomarkers — Neill R. Graff-Radford, M.D.

The Lewy Body Dementia Association (LBDA) has designated Mayo Clinic as a Research Center of Excellence (RCOE). The LBDA has identified leading clinicians for advanced diagnosis and treatment and who are committed to providing advanced care, community outreach and support.

Clinical studies

Ongoing clinical studies in Lewy body dementia at Mayo Clinic's campus in Jacksonville, Florida include:

• A Study of Change in Imaging Biomarkers of Dementia with Lewy Bodies (DLB) and Associations with Cognitive and Functional Decline
• A Study to Identify and Characterize Neurophysiological Biomarkers for Progression of Neurodegenerative Disease
• Mayo Clinic Lewy Body Disease Functional Genomics Program. Funded by Mayo Clinic, Dr. Ross and Dr. Boeve lead this program which collects genetic material, skin biopsies and other biomarkers from people with Lewy body dementia.