Rochester, Minnesota Clinical Profile


Jonathan Graff Radford, M.D., studies normal aging, mild cognitive impairment, cerebrovascular disease and neurodegenerative disorders. Specific disorders of interest include mild cognitive impairment, vascular cognitive impairment, Alzheimer's disease, Lewy body dementia, corticobasal syndrome, posterior cortical atrophy and frontotemporal dementia.

Dr. Graff Radford collaborates with colleagues in neuroradiology and neuropathology to characterize individuals with cognitive impairment. He is a co-investigator in the Mayo Clinic Alzheimer's Disease Research Center and the Mayo Clinic Study of Aging.

Focus areas

  • Vascular contributions to dementia
  • Clinical course and neuroimaging features of Lewy body dementia
  • Neuroimaging biomarkers in dementia
  • Normal pressure hydrocephalus

Significance to patient care

Dr. Graff Radford's research is focused on identifying therapeutic targets for cognitive impairment, improving diagnostic accuracy of cognitive disorders.

Professional highlights

  • Myron and Jane Hanley Career Development Award in Stroke Research, Mayo Clinic, 2015-2018

Clinical Studies

See my clinical studies


See my publications


Primary Appointment

  1. Consultant, Department of Neurology

Academic Rank

  1. Associate Professor of Neurology


  1. Fellow Stroke/Cerebrovascular, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. Fellow - Behavioral Neurology Behavioral Neurology, Programs in Florida, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Postdoctoral Certificate - Clinical and Translational Science Mayo Clinic College of Medicine
  4. MD University of Florida
  5. BS - Basic biological and medical sciences University of Florida

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