Clinicopathological Studies

Dr. Graff-Radford established the Mayo Clinic Brain Bank in 1991 on Mayo Clinic's Florida campus after more than 500 cases and controls to autopsy. The Mayo Clinic Brain Bank has continued to grow to more than 12,000 specimens. It is currently led by Dennis W. Dickson, M.D.

Drs. Graff-Radford and Dickson have co-authored more than 200 scientific publications, including studies showing that:

  • Posterior cortical atrophy is most often due to Alzheimer's disease.
  • Hippocampal sclerosis can be mistaken for Alzheimer's disease clinically.
  • Alzheimer's disease pathology can be grouped into typical, limbic and hippocampal sparing, and the clinical picture and progression differs between these groups.

Related publications