Researchers in Dr. Graff-Radford's Memory Disorders Lab are discovering new biomarkers. These findings include a study that links plasma Ab levels to an area on chromosome10. We also reported the hereditary factors related to plasma A and the risk of developing dementia as there is a drop in the plasma A42 while A40 remains high. With Rosa Rademakers, Ph.D., we have shown that the progranulin levels are an excellent way to detect progranulin mutations. We are working alongside a consortium with Sid O'Bryant, Ph.D. to standardize plasma biomarkers. We have also published a set of proteins that can distinguish Lewy body dementia from Alzheimer's disease and controls.

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