Overview

The Department of Biochemistry and Molecular Biology at Mayo Clinic makes significant contributions to the Mayo Clinic mission through nationally and internationally recognized biomedical research and the training of students, fellows and clinicians.

The department is Mayo's largest discovery science department. The faculty have expertise in a number of areas including aging, cancer biology and metastasis, cell biology, cardiovascular and pulmonary diseases, DNA structure and repair, genetics and genomics, GI and liver disease, musculoskeletal conditions, polycystic kidney disease, structural biology and virology. Biochemistry and Molecular Biology laboratories use human cells and tissues, as well as animal model systems (including rodents, zebrafish, Drosophila, Caenorhabditis elegans, yeast and bacteria) to dissect complicated biological questions and find answers to human disease.

In addition to conducting outstanding research, faculty members direct and maintain many of the Mayo Clinic institutional core facilities, providing state-of-the-art technology for all scientists and clinicians at Mayo Clinic in the areas of cryoelectron microscopy (CryoEM), microscopy (EM, light sheet, multi-photon), nuclear magnetic resonance spectroscopy and imaging, proteomics and mass spectroscopy, genomics and molecular biology, and knockout mouse technology. These facilities form an essential part of the Mayo Clinic research base.

The department fosters the education of future leaders in biomedical sciences through the Mayo Clinic Graduate School of Biomedical Sciences. The Biochemistry and Molecular Biology track is organized into three subtracks: biochemistry and structural biology, cell biology and genetics, and cancer biology. The Regenerative Sciences track is focused on developmental biology and tissue regeneration. Department members contribute significantly to the core didactic graduate-level education of all Mayo Clinic Graduate School of Biomedical Sciences doctoral students in molecular cell biology, genome biology, genetics, biochemistry, mechanisms of disease and a series of advanced graduate tutorials that provides an important extension to the core curriculum.

Publications

Department for Biochemistry and Molecular Biology investigators are internationally recognized scientists whose work is published in leading scientific journals.

View individual faculty research biographies to see a list of publications

Use the Mayo Clinic Publications Database to search specific topics or authors.

Search the Mayo Clinic database