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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-9 of 9 for Pediatric brain tumors

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  • Study status: Open/Status Unknown
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  1. Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

    Rochester, MN

  2. Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

    Rochester, MN

  3. Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

    Rochester, MN

  4. Cognitive Function After Treatment of Primary CNS Malignancy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Neuropsychological and Behavioral Testing in Young Patients with Cancer

    Rochester, MN

  6. A Study to Develop Liquid Biopsy for Pediatric Brain Tumor Patients

    Rochester, MN

  7. A Registry Called Every Child for Collecting Data and Biology Specimens on Younger Patients with Cancer

    Rochester, MN

  8. A Registry for Children Treated with Proton Radiation Therapy

    Rochester, MN

  9. Developing Criteria for Treatment of Neurofibromatosis Type 1 Associated Optic Pathway Glioma

    Rochester, MN


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