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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for Upper endoscopy

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  1. A Study Using the Esophageal Sponge to Gather Specimens for Management of Dietary Therapy in Eosinophilic Esophagitis

    Rochester, MN

    A Study Using the Esophageal Sponge to Gather Specimens for Management of Dietary Therapy in Eosinophilic Esophagitis

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    The purpose of this study is to see if the cytosponge ( a 10 minute, in office procedure that does not require sedation) can be used to replace the 6-10 endoscopies that are routinely performed during the standard of care dietary restriction and food reintroduction trials to manage eosinophilic esophagitis.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Open for enrollment

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 15-004741

    • NCT ID:

      NCT02599558

    • Sponsor Protocol Number:

      15-004741

  2. Quality of Life After Endoscopic Skull Base Surgery

    Rochester, MN

    Quality of Life After Endoscopic Skull Base Surgery

    • Location:

      Observational What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    The goal of this study is to determine the olfactory outcomes and quality of life outcomes associated with cautery upper limb vs cold knife upper limb nasal septal incision.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Closed for enrollment

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 15-008207

    • Sponsor Protocol Number:

      15-008207

  3. Minimal Risk Registry of Endoscopic Image and Pathology Correlation for Fujiflim

    Jacksonville, FL, Rochester, MN

    Minimal Risk Registry of Endoscopic Image and Pathology Correlation for Fujiflim

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    The purpose of this study is to see if advanced endoscopic imaging may be helpful to accurately distinguish pathological tissue from normal tissue and guide therapy of endoscopically identified pathology.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Open for enrollment

    		View complete study & contact information

    Jacksonville, Fla.

    Open for enrollment
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 17-002101
      • Jacksonville, Florida: 17-002101

    • NCT ID:

      NCT03440047

    • Sponsor Protocol Number:

      17-002101

  4. A Study Developing a Rapid Count for Total Bacteria in Human Intestinal Fluid

    Scottsdale/Phoenix, AZ

    A Study Developing a Rapid Count for Total Bacteria in Human Intestinal Fluid

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    The purpose of this study is to develope a rapid lab test for counting total bacteria in human intestinal fluid collected by aspiration from the duodenal section of the small intestine.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Scottsdale/Phoenix, Ariz.

    Closed for enrollment

    		View complete study & contact information
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    Study IDs

    • Site IRB:

      • Scottsdale/Phoenix, Arizona: 15-009608

    • Sponsor Protocol Number:

      15-009608

  5. Endoscopic Multimedia Information System

    Rochester, MN

    Endoscopic Multimedia Information System

    • Location:

      Observational What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    This study aims to develop an Endoscopic Multimedia Information System (EMIS) to capture high quality endoscopy videos, analyze the captured videos for important contents, and provide efficient access to these contents.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Closed-enrolling by invitation

    What is this? (?)

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 07-007614

    • Sponsor Protocol Number:

      07-007614

  6. A Study to Compare the Effectveness of Colon Capsule Endoscopy versus Computed Tomographic Colonography in Screening to Identify Colon Polyps

    Rochester, MN

    A Study to Compare the Effectveness of Colon Capsule Endoscopy versus Computed Tomographic Colonography in Screening to Identify Colon Polyps

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    • Study phase:

      I What is this?
      During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

    About this study

    The purpose of this study is to compare the effectiveness of Colon Capsule Endoscopy versus Computed Tomographic Colonography for the screening of colon polyps in the usual screening population.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Closed for enrollment

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 16-000798

    • NCT ID:

      NCT02754661

    • Sponsor Protocol Number:

      COVGIC20543

  7. Electronic Nose Identification of Fasting and Non-fasting Breath Profiles

    Rochester, MN

    Electronic Nose Identification of Fasting and Non-fasting Breath Profiles

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    The investigators will study a noninvasive no risk process by which the investigators can quickly screen and assess for fasting and non-fasting states in individuals scheduled for routine endoscopy.

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Closed-enrolling by invitation

    What is this? (?)

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 14-009226

    • NCT ID:

      NCT02419976

    • Sponsor Protocol Number:

      14-009226

  8. Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet

    Rochester, MN

    Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet

    • Location:

      Interventional What is this?

      Describes the nature of a clinical study. Types include:

      • Observational study — observes people and measures outcomes without affecting results.
      • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
      • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

    About this study

    Does the small bowel microbiota in healthy individuals change after consumption of a Western diet?

    Participating Mayo Clinic locations

    Study statuses change often. Please contact us for help.

    Mayo Clinic Location Status Contact

    Rochester, Minn.

    Closed for enrollment

    		View complete study & contact information
    Print study details

    Study IDs

    • Site IRB:

      • Rochester, Minnesota: 16-006388

    • NCT ID:

      NCT03266536

    • Sponsor Protocol Number:

      16-006388
.

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