A Study to Evaluate Volumetric Laser Endomicroscopy with Intelligent Real-time Image Segmentation (IRIS)

Overview

About this study

The purpose of this study is to examine how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric Laser Endomicroscopy).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

18 years of age or older at the time of informed consent.
Barrett's esophagus greater than 2 cm in length.
Undergoing a scheduled upper endoscopy with VLE exam for surveillance as standard of care.

Exclusion Criteria:

Less than 18 years old at the time of informed consent.
Unable to provide written informed consent.
Esophageal stenosis/stricture preventing VLE.
Esophagitis.
Severe medical comorbidities preventing endoscopy.
Pregnancy.
Uncontrolled coagulopathy.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Cadman Leggett, M.D.	Closed for enrollment
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Francisco Ramirez, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Cadman Leggett, M.D.

Closed for enrollment

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Francisco Ramirez, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials