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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 46 for Parkinson's disease

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  1. A Trial of 18F-AV-133 Positron Emission Tomography (PET) Imaging to Differentiate Subjects with Parkinson's Disease (PD) from other Movement Disorders

    Scottsdale/Phoenix, AZ

  2. A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of GZ/SAR402671 in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

    Scottsdale/Phoenix, AZ

  3. DaTSCAN Imaging in Aging and Neurodegenerative Disease

    Rochester, MN

  4. ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study)

    Scottsdale/Phoenix, AZ

  5. A Study Evaluating Deep Brain Stimulation for Treating Parkinson's Patients with Insomnia

    Jacksonville, FL

  6. A Study Evaluating Nelotanserin for Treatment of Visual Hallucinations in Subjects with Lewy Body Dementia

    Rochester, MN

  7. High Frequency Oscillations in Neurologic Disease

    Rochester, MN

  8. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study, with an Active-Treatment Dose-Blinded Period, to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Subjects with Parkinson’s Disease

    Jacksonville, FL

  9. Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease

    Jacksonville, FL

  10. Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth

    Scottsdale/Phoenix, AZ

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