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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 48 for Parkinson's disease

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  1. A Study to Provide Feasibility Data for a Novel Method of Defining Patient-Specific Functional Anatomic Targets for Globus Pallidus Internus (GPi) Deep Brain Stimulation (DBS) Placement

    Jacksonville, FL

  2. Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease

    Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate Quantitative Phenotypes of Movement Disorders

    Jacksonville, FL

  4. A Study of the Effect of Deep Brain Stimulation on Constipation and Anosmia in Parkinson Disease

    Rochester, MN

  5. A Study of Biofluids in Parkinson Disease and Related Disorders

    Rochester, MN

  6. Gastrointestinal Lewy Bodies: A Cause or Effect of Parkinson’s Disease?

    Jacksonville, FL

  7. Anti-Bullous Pemphigoid Antibodies in Patients with Neurological Disease

    Rochester, MN

  8. Systemic Synuclein Sampling Study (S4)

    Scottsdale/Phoenix, AZ

  9. Magnetic Resonance Elastography of Dementia

    Rochester, MN

  10. Neurological Diseases Co-existing in Patients with Spasmotic Dsyphonia (SD)

    Jacksonville, FL

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