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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 48 for Parkinson's disease

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  1. Open-Label Safety Study of ADS-5102 in PD Patients With LID

    Scottsdale/Phoenix, AZ

  2. A Study to Evaluate the Effectiveness, Safety, and Tolerability of NLY01 in Early-stage Parkinson's Disease

    Scottsdale/Phoenix, AZ

  3. Transcutaneous Submandibular Gland Biopsy: Feasibility of Repeat Biopsy as a Progression Marker for Parkinson's Disease

    Scottsdale/Phoenix, AZ

  4. Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes

    Scottsdale/Phoenix, AZ

  5. A Study to Examine the Long-Term Safety, Tolerability and Effectiveness of APL-130277 for the Acute Treatment of "OFF" Episodes in Patients with Parkinson's Disease

    Scottsdale/Phoenix, AZ

  6. A Phase 3 Study to Examine the Effectiveness, Safety and Tolerability of APL-130277 for the Acute Treatment of Motor Fluctuation Episodes in Patients with Parkinson's Disease

    Scottsdale/Phoenix, AZ

  7. Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation

    Jacksonville, FL

  8. A Study of Inosine Treatment to Slow Clinical Decline in Patients with Parkinson's Disease

    Scottsdale/Phoenix, AZ

  9. A Pivotal Clinical Trial of the Management of the Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Idiopathic Parkinson's Disease

    Rochester, MN

  10. Neurotransmitter Measurements Using Wireless Instantaneous Neurotransmitter Concentration System (WINCS) During Deep Brain Stimulation Neurosurgery

    Rochester, MN

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