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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 124 for transplant

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  • Study status: Open/Status Unknown
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  1. J&J Vaccine Booster in Transplant Recipients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study to Verify the Application of Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Asymptomatic Lung Transplant Recipients

    Jacksonville, FL

  3. Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. A Study to Evaluate Posoleucel ALVR105 to Treat Kidney Transplant Recipients with BK Viremia

    Scottsdale/Phoenix, AZ

  5. A Study to Evaluate the Effectiveness and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients

    Rochester, MN

  6. Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

    Rochester, MN

  7. Mediterranean Diet Post-liver Transplantation

    Rochester, MN

  8. Daratumumab in Cardiac AMR & HLA Desensitization Prior to Transplantation

    Rochester, MN

  9. A Study to Evaluate the Safety and Effectiveness of Pegcetacoplan to Treat Post-Transplant Recurrence of C3G or IC‑MPGN

    Scottsdale/Phoenix, AZ

  10. A Study to Assess Older Adults Applying Pre-transplant Comorbidity, Geriatric Assessment and Biomarkers to Predict Non-Relapse Mortality After Allogeneic Transplant (CHARM)

    Rochester, MN, Scottsdale/Phoenix, AZ

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