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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 111-120 of 2195 for surgery

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  1. A Study of Hypofractionated Radiotherapy to the Whole Breast Alone Before Breast Conserving Surgery

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  2. Open Vs Robotic-Assisted Radical Cystectomy: A Randomized Trial

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study

    Rochester, MN

  4. Robotic vs. Open NSM for Early Stage Breast Cancer

    Jacksonville, FL, Rochester, MN

  5. ESG Use for Weight Loss in Obese UC Patients Undergoing Colectomy With IPAA

    Rochester, MN

  6. A Study to Analyze Surgical Outcomes and Predictors of Treatment for Hip Diseases

    Rochester, MN

  7. Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)

  8. A Study of Computer Simulation of Endovascular Repair of Cerebral Aneurysms Aneurysms

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy

    Rochester, MN

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