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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 111-120 of 2031 for surgery

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  1. A Study to Evaluate Virtual Remote Control Robotic Percutaneous Coronary Intervention

    Rochester, MN

  2. A Study of Fluorine F 18 Fluorodopa-Labeled PET Scans for Planning Surgery and Radiation Therapy to Treat Patients who have Newly Diagnosed High- or Low-Grade Glioma Brain Cancer Tumors

    Rochester, MN

  3. A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting

    Albert Lea, MN

  4. Higher Per Daily Treatment-Dose Radiation Therapy Or Standard Per Daily Treatment Radiation Therapy In Treating Patients With Early-Stage Breast Cancer That Was Removed By Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Patient-Centered Outcomes In The Surgical Treatment Of Uterovaginal Prolapse

    Jacksonville, FL, Rochester, MN

  6. Evaluating The Benefit Of Concurrent Tricuspid Valve Repair During Mitral Surgery

    Rochester, MN

  7. Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

  8. Standard Or Comprehensive Radiation Therapy In Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy And Surgery

    Albert Lea, MN, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  9. A Study to Evaluate NextScience® Xperience™ versus Normal Saline Irrigation Solution for Decreasing Bioburden After Primary Total Hip and Knee Arthroplasty

    Jacksonville, FL

  10. A Study for Cerebral Open Flow Microperfusion

    Rochester, MN

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