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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 388 for sleep

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  1. Sleep Apnea After Anterior Cervical Discectomy and Fusion

    Jacksonville, FL

  2. Sleep Restriction and Obesity

    Rochester, MN

  3. Addressing Sleep Problems in Older Adults

    Rochester, MN

  4. A Study of a Neuromodulation Therapy Device for the Treatment of Sleep Apnea

    Rochester, MN

  5. A Study of the Effects of Sleep on Human Microbiota and the Implications for Health and Disease

    Rochester, MN

  6. Obstructive Sleep Apnea and Chronic Cough

    Jacksonville, FL

  7. Sleep Apnea and Vascular Function

    Rochester, MN

  8. This Study Assesses the Impact of Different Sheets on Body Temperature and Sleep

    Rochester, MN

  9. A Study of a Sleep Health ‘App’ to Help First-Time Users of Positive Airway Pressure Therapy for Sleep Apnea

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

    Rochester, MN

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