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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 68 for pediatric AND surgery

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  1. A Study to Collect Data Elements Related to Pediatric Epilepsy Surgery

    Rochester, MN

  2. A Study of Effect of Different Biochemical Markers including Leptin and Spexin in Children Before and After Having Hypothalamus Surgery

    Rochester, MN

  3. A Study to Evaluate Time to First Movement for Fetal Surgery Patients Injected with Intramuscular Anesthesia

    Rochester, MN

  4. A Study to Evaluate Maternal-fetal Immune Responses to Fetal Surgery

    Rochester, MN

  5. A Study to Establish a Pediatric Spine Registry

    Rochester, MN, Minneapolis, MN

  6. A Study of Noninvasive Hemoglobin Monitoring in Pediatric Patients Undergoing Orthopedic Surgery

    Rochester, MN

  7. Thrombin Generation before and after Cardiopulmonary Bypass in Pediatric Patients

    Rochester, MN

  8. A Study of Characteristics and Post-surgical Outcomes of Pediatric Patients Diagnosed with Lipoblastoma

    Rochester, MN

  9. Utilization of Blackbone MRI in a Pediatric Population

    Rochester, MN

  10. Growth, Development and Quality of Life in Pediatric Patients after Cone Reconstruction for Ebstein Anomaly

    Rochester, MN

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