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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 69 for pediatric AND surgery

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  1. Fontan Extra-Cardiac Conduit Stenosis and Stent Placement

    Rochester, MN

  2. A Study to Assess Asymptomatic Adolescents with Limited Hip Range of Motion

    Rochester, MN

  3. Long-term Results of Proximal Row Carpectomy in Younger Patients

    Rochester, MN

  4. A Study to Discover and Validate Candidate Genes in Pectus Excavatum

    Scottsdale/Phoenix, AZ

  5. Adolescents with Brachial Plexus Birth Palsy (BPBP)

    Rochester, MN

  6. Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

    Rochester, MN, Minneapolis, MN

  7. A Study to Learn More About Children Before and After Liver Transplant

    Rochester, MN

  8. A Study to Establish An Adolescent Idiopathic Scoliosis Outcomes Database Registry

    Rochester, MN

  9. Hearing Genomics

    Rochester, MN

  10. A Study of Molecular Characterization of Spinal Tissue

    Rochester, MN

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